In-depth guides written by a practicing doctor — explaining the science behind every calculator, drug, and clinical decision tool on RxMedCalc.
Naegele's rule, ultrasound dating, IVF EDD, trimester milestones, India's antenatal scan schedule (NT, TIFFA, GDM screening), government schemes (PMMVY, JSY, JSSK), and signs of labour.
Working backwards from EDD or LMP, fertile window and ovulation timing, IVF vs natural conception dating, and what conception date means for gestational age accuracy.
All 5 components with scoring table, 1-minute vs 5-minute significance, NRP resuscitation protocol, what low scores mean for parents, and APGAR in premature babies.
Physiological vs pathological jaundice, AAP 2022 updated phototherapy thresholds by age and gestational age, G6PD in India, kernicterus prevention, and warning signs for parents at home.
Drug dosing with CrCl, IBW in obese patients, CrCl vs eGFR explained, dose thresholds for vancomycin, DOACs, metformin, aminoglycosides, and AKI considerations.
CKD-EPI 2021, why race was removed, G1–G5 and A1–A3 staging, SGLT2 inhibitors in CKD, nephrotoxins to avoid, and when to refer to nephrology.
Albumin-corrected calcium formula, ionised vs total calcium, causes of hypocalcaemia and hypercalcaemia, calcium in CKD, and when to check PTH and vitamin D.
What each point means, when to anticoagulate, full DOAC comparison, HAS-BLED bleeding risk, warfarin indications, paroxysmal vs permanent AFib, and common myths debunked.
How Framingham calculates 10-year ASCVD risk, statin thresholds, LDL targets by risk category, limitations in South Asians, and newer risk enhancers like CAC score and hs-CRP.
GRACE 2.0 variables, in-hospital vs 6-month mortality, GRACE vs TIMI vs HEART score, early invasive vs conservative strategy, antiplatelet and anticoagulation decisions.
MAP formula, normal range, MAP in septic shock (target ≥65 mmHg), vasopressor thresholds, MAP vs systolic BP in clinical decisions, and MAP in raised intracranial pressure.
Bedside scoring, 30-day mortality table, CRB-65 for primary care, antibiotic selection by severity, investigations to order, ICU criteria, and Klebsiella in Indian patients.
All 7 physiological parameters, score thresholds and escalation triggers, NEWS2 vs MEWS, use in COVID-19 and sepsis, and how nursing teams use it for triage on wards.
TBSA, Rule of Nines, 8-hour vs 16-hour timing, Modified Brooke comparison, urine output targets, paediatric burns, fluid creep warning, and the most common clinical mistakes.
Shock index formula (HR÷SBP), normal vs abnormal values, use in trauma, PPH, ectopic pregnancy, and MI, modified shock index, and limitations in elderly and hypertensive patients.
WHO ORS composition, Plan A/B/C dehydration management, volumes by weight and age, home-made ORS preparation, rice ORS, Zinc supplementation, and when to escalate to IV fluids.
Why "at risk" starts at BMI 23 for Indians, the thin-fat Indian phenotype, visceral adiposity, waist circumference thresholds, BMI limitations, and a full metabolic risk assessment guide.
DCCT % vs IFCC mmol/mol conversion, HbA1c targets by age and comorbidity, estimated average glucose (eAG), HbA1c unreliability in haemoglobinopathies and CKD, and fructosamine as alternative.
Full equivalence table (prednisolone, dexamethasone, hydrocortisone, methylprednisolone, betamethasone), anti-inflammatory vs mineralocorticoid potency, tapering principles, and adrenal suppression risk.
Scoring E/V/M in detail, GCS severity classification (mild/moderate/severe TBI), the intubated T-modifier, Adelaide paediatric scale, reversible causes of low GCS, and the "drop of 2" red flag rule.
ABCD² scoring variables, 2-day and 7-day stroke risk by score, the critical 48-hour investigation window, dual antiplatelet therapy, carotid imaging urgency, and TIA mimics to exclude.
DVT and PE pre-test probability scoring, when to use D-Dimer vs direct imaging, age-adjusted D-Dimer, CTPA vs ultrasound pathways, DOAC treatment, and duration of anticoagulation.
Mentzer index formula (MCV÷RBC), IDA vs beta-thalassaemia trait cut-off, sensitivity and specificity, other discriminant indices (England-Fraser, Shine-Lal), and next steps when the index is borderline.
Full 6-organ SOFA scoring table, Sepsis-3 definition, ICU mortality by score, delta-SOFA trend analysis, qSOFA bedside screening, and the Hour-1 sepsis bundle.
Three-variable bedside qSOFA (RR, GCS, SBP), sensitivity vs specificity trade-offs, qSOFA vs SIRS vs NEWS2, when a score of ≥2 should change your management, and the Sepsis-3 flowchart.
AG formula, albumin correction, HAGMA vs NAGMA causes, delta ratio for mixed disorders, Winter's formula for respiratory compensation, and step-by-step ABG interpretation.
MELD and MELD-Na formulas, 3-month mortality by score, MELD 3.0 with sex variable, transplant listing thresholds in India, TIPS candidacy, and what the score means for patients' families.
4-2-1 rule vs daily volume method, fluid choice (0.9% saline vs 0.45% saline, dextrose concentration), hyponatraemia risk in hospitalised children, and NICE guidance on isotonic fluids.
Clinical signs of mild/moderate/severe dehydration, WHO dehydration assessment scale, Plan A/B/C rehydration, when to use IV vs oral route, and red flags that need hospital admission.